Munich Sequencing Alliance -

Munich Sequencing Alliance

Shaping the Future of Genomic Research in Munich

  • Facilitating precision medicine for patients
  • Providing cutting edge sequencing infrastructure
  • Enabling genome research in Munich

Applying next generation sequencing methods on a large scale, we have joined an international group of centers which specialize in the identification of mutations causing common and rare disorders. This allows us to diagnose patients with formerly unknown diseases and develop new treatment strategies. Moreover, we are able to uncover genetic risk factors for complex genetic diseases.

This knowledge, together with researching environmental and lifestyle risk factors, will enable us to improve our patients’ well-being and health by paving the way to precise and individualized therapies.

The access to this technology further drives research advances in neuroscience, cardiology and cancer research - besides many other applications. Indeed, its fundamental importance reaches beyond the medical sciences as it provides unprecedented insight into the comparative genetic architecture of plants and animals, with revolutionary impacts on agriculture and other areas.

Member Institutions:

Mission

The Munich Sequencing Alliance was founded by the Helmholtz Zentrum München, the Technical University of Munich, the Ludwig-Maximilians Universität, and the Max-Planck Institute for Psychiatry to enable large-scale sequencing projects in the Munich area.


Platform
Sequencing is performed on Illumina HiSeq 4000 machines. Currently, two machines produce an output of 10 billion reads over 3.5 days, yielding about 3000 gigabases per run. The platform supports multiplexing and sequencing of any Illumina libraries. Library preparation is also offered for example for genome-sequencing, exome sequencing, and RNA-sequencing applications. The platform also provides bioinformatics support including sequencing quality control, alignment to reference genomes, variant calling and annotation.

 

Usage
Projects of any scale are supported, with priority given to the larger ones. We accept requests from any institution, but priority and reduced pricing are offered to the member institutions. Send your sequencing request to sequencingnoSp@m@helmholtz-muenchen.de, specifying your host institution, the number of samples, and sequencing type.  We are also glad to collaborate with you to design your sequencing experiments and to analyse the data. 

 

Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg        

Ludwig-Maximilians-Universität München (LMU)
Geschwister-Scholl-Platz 1
80539 München

Technischen Universität München (TUM)
Arcisstr. 21
80333 München

Max-Planck-Institut für Psychiatrie
Kraepelinstraße 2-10
80804 Münche

Host:

Prof. Thomas Meitinger and
Prof. Juliane Winkelmann

Helmholtz Zentrum München

Coordinator:

LMU:
Prof. Martin Reincke

TUM:
Prof. Heribert Schunkert

Helmholtz Zentrum München:
Prof. Juliane Winkelmann

MPI für Psychiatrie:
Dr. Dr. Elisabeth Binder

Contact Person:

Platform Manager:

PD Dr. Tim Strom
Helmholtz Zentrum München

Technology:

Dr. Elisabeth Graf

Contact:

E-mail

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